Aph 1b Antibody

Product no.: APH1B-101AP

General Information

 

 

Product

 

Aph 1b Antibody

Description

Affinity Purified Presenelin-stabiliziation factor-like Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

C. elegans, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 235-257 of Human Presenilin stabilizing protein.

Specificity APH1B-101AP does not cross react to other component of gamma secretase complex nor with other proteins.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500


Protein

 

 

Uniprot #

 

Q8WW43

Overview

Subunit of gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and beta-amyloid precursor protein.

Molecular Function

Notch signaling pathway

Subcellular Location

Membrane; Multi-pass protein

Expression

Weakly expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle, heart, and brain.

Structure

Component of gamma-secretase complex.  Interacts with PSEN1 and PSEN2.

Alternative Nomenclature

Anterior pharynx defective 1B like antibody

Gamma secretase subunit APH 1B antibody

Presenilin stabilisation factor like antibody

PRO1328 antibody

PSFL antibody

TAAV 688 antibody

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
Aph 1b Antibody FITC Aph 1b Antibody FITC
APH1B-FITC
Aph 1b Antibody BIOTIN Aph 1b Antibody BIOTIN
APH1B-BIOTIN
Aph 1b Blocking Peptide Aph 1b Blocking Peptide
P-APH1B
Aph 1b Positive Control Aph 1b Positive Control
PC-APH1B
Display accessory details

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