ASF1A Antibody

Product no.: ASF1A-101AP

General Information

 

 

Product

 

ASF1A Antibody

Description

Affinity Purified Histone Chaperone ASF1A Antibody

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 60-120 on human AF1A protein.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.58 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunohistochemistry 1:50-1:100

Immunoprecipitation

1:150

Western Blot

1:500


Protein

 

Uniprot #

 

Q9Y294

Overview

Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Molecular Function

Transcription regulation

Subcellular Location

Nucleus

Structure

Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with CABIN1, HAT1, HIRA, NASP, TAF1, TLK1, TLK2 and UBN1. Interacts with CDAN1. Found in cytosolic coplex with CDAN1, ASF1B, IPO4 and histones H3.1 and H4. Interacts with CREBBP.

Alternative Nomenclature

Anti silencing function 1A antibody

asf1a antibody

CCG1-interacting factor A antibody

CGI 98 antibody

CIA antibody

hAsf1 antibody

hAsf1a antibody

hCIA antibody

Histone chaperone ASF1A antibody

HSPC146 antibody

Hypothetical protein FLJ22085 antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
ASF1A Antibody FITC ASF1A Antibody FITC
ASF1A-FITC
ASF1A Antibody BIOTIN ASF1A Antibody BIOTIN
ASF1A-BIOTIN
ASF1A Blocking Peptide ASF1A Blocking Peptide
P-ASF1A
ASF1A Positive Control ASF1A Positive Control
PC-ASF1A
Display accessory details

Browse these categories as well: Histones, Primaries, DNA Damage Response, Chromatin Modifying Enzymes, Chaperones