Axl Antibody BIOTIN

General Information

Product

Axl Antibody BIOTIN-Conjugated

Description

BIOTIN-Conjugated AXL receptor tyrosine kinase UFO isoform 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 840-880 on mouse AXL protein. The peptide was post translationally modified to acheive proper orientation and antigenicity.

Accession #

NCBI:  NP_033491

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59-0.65 µg/µl in antibody stabilization buffer

Form

BIOTIN-Conjugated

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q00993

Overview

Receptor tyrosine kinase that transduces signals from the ECM into cytoplasm by binding growth factor GAS6. Regulates survival, proliferation, migration and differentiation.

Molecular Function

ATP-binding, Nucleotide binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase, Immunity Differentation and Innate Immunity

Subcellular Location

Cell membrane; Single-pass type II membrane protein

Expression

Developing tissues in late embryogenesis. In cells forming organ capsules as well as in connective tissue structures in adult.

Structure

Heterodimer and heterotetramer with ligand GAS6.

Alternative Nomenclature

Adhesion related kinase antibody

Ark antibody

Tyro7 antibody

Tyrosine protein kinase receptor UFO antibody