BMPR1A Antibody

Product no.: BMPR1A-101AP
$285.00


General Information

 

 

Product

 

BMPR1A Antibody

Description

Affinity Purified Bone morphogenetic protein receptor type-1A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 460-510 on human Bone morphogenetic protein receptor type-1A.

Accession #

NCBINP_004320


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

ELISA

 

1:10,000

Immunohistochemistry 1:150

Immunoprecipitation

1:150

Western Blot

1:500


Protein

 

Uniprot #

 

P36894

Overview

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

Molecular Function

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Highly expressed in skeletal muscle.

Structure

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

Contains 1 GS domain.

Contains 1 protein kinase domain.

Alternative Nomenclature

Activin A receptor type II like kinase 3 

Activin receptor like kinase 3 

ACVRLK 3

ALK 3 

BMP type-1A receptor 

BMPR 1A 

Bmpr 

Bone morphogenetic protein receptor type-1A

BR1a

CD292 

Serine threonine protein kinase receptor R5

SKR5 

zBMPR IA

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
BMPR1A Antibody BIOTIN BMPR1A Antibody BIOTIN
BMPRA1-BIOTIN $375.00 *
BMPR1A Antibody FITC BMPR1A Antibody FITC
BMPRA1-FITC $375.00 *
BMPR1A Blocking Peptide BMPR1A Blocking Peptide
P-BMPRA1 $155.00 *
BMPR1A Positive Control BMPR1A Positive Control
PC-BMPRA1 $200.00 *
Display accessory details

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