BST2 Antibody

Product no.: BST2-212AP

$320.00

Description
Publications

General Information
Product	BST2 Antibody
Description	Affinity Purified Bonemarrow stromal antigen 2 Antibody Mid-Region
Verified Applications	ELISA, CM, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Mid-Region Epitope Synthetic peptide taken within amino acid region 50-100 on human Bonemarrow stromal antigen 2 protein.
Accession #	GenBank: BAD96844
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.62 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	Mid-Region
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:2,000
ELISA	1:2,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Immunoprecipitation	1:200
Western Blot	1:500-1:1,000
Protein
Uniprot #	Q10589
Overview	IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.
Molecular Function	Antiviral defense; B-cell activation; Immunity; Innate immunity
Subcellular Location	Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane
Expression	Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.
Structure	Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.
Alternative Nomenclature	Bone marrow stromal antigen 2 antibody Bone marrow stromal cell antigen 2 antibody BST 2 antibody CD 317 antibody CD317 antigen antibody HM1.24 antigen antibody NPC A 7 antibody Tetherin antibody

Protein information supplied by UniProt