BTK Antibody

Product no.: BTK-101AP

$285.00

Description

General Information
Product	BTK Antibody
Description	Affinity Purified Bruton's Tyrosine Kinase Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey, Mouse, Pig, Rat
Immunogen	Synthetic peptide taken within amino acid region 550-650 on human BTK protein.
Accession #	NCBI: NP_000052.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.66 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DOT Blot	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q06187
Overview	Non-receptor tyrosine kinase invovled in B lymphocyte development.
Molecular Function	Kinase; Transferase; Tyrosine-protein Kinase
Subcellular Location	Cytoplasm; Cell Membrane; Peripheral membrane: Nucleus. In steady state BTK is predominantly cytosolic.
Expression	B-lymphocytes
Structure	PH domain mediates binding to inositol polyphosphate and phosphoinositides, leading to its targeting with plasma membrane. Extended in the BTK kinase family by a region designated Tec homology domain, which has roughly 80 residues preceding SH3 domain.
Alternative Nomenclature	Agammaglobulinaemia tyrosine kinase antibody AGMX 1 antibody AT antibody ATK antibody B cell progenitor kinase antibody BPK antibody Bruton tyrosine kinase antibody Btk antibody IMD1 antibody PSCTK 1 antibody Tyrosine protein kinase BTK antibody XLA antibody Agammaglobulinaemia tyrosine kinase antibody AGMX 1 antibody AT antibody ATK antibody B cell progenitor kinase antibody BPK antibody Bruton tyrosine kinase antibody Btk antibody IMD1 antibody PSCTK 1 antibody Tyrosine protein kinase BTK antibody XLA antibody

Protein information supplied by UniProt