|
General Information
|
|
|
Product
|
BTK Antibody FITC-Conjugated
|
|
Description
|
FITC-Conjugated Bruton's Tyrosine Kinase Antibody
|
|
Verified Applications
|
ELISA, IHC, IP, WB
|
|
Host
|
Rabbit
|
|
Species Cross Reactivity
|
Human, Monkey, Mouse, Pig, Rat
|
|
Immunogen
|
Synthetic peptide taken within amino acid region 550-650 on human BTK protein.
|
|
Accession #
|
NCBI: NP_000052.1
|
|
Physical Properties
|
|
|
Quantity
|
100 µg
|
|
Volume
|
200 µl
|
|
Concentration
|
0.66 µg/µl in antibody stabilization buffer
|
|
Form
|
FITC-Conjugated
|
|
Clonality
|
Polyclonal
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
|
DOT Blot
|
1:10,000
|
|
ELISA
|
1:10,000
|
| Immunohistochemistry |
1:50-1:150 |
| Immunoprecipitation |
1:200 |
|
Western Blot
|
1:500
|
|
Protein
|
|
|
Uniprot #
|
Q06187
|
|
Overview
|
Non-receptor tyrosine kinase invovled in B lymphocyte development.
|
|
Molecular Function
|
Kinase; Transferase; Tyrosine-protein Kinase
|
|
Subcellular Location
|
Cytoplasm; Cell Membrane; Peripheral membrane: Nucleus. In steady state BTK is predominantly cytosolic.
|
|
Expression
|
B-lymphocytes
|
|
Structure
|
PH domain mediates binding to inositol polyphosphate and phosphoinositides, leading to its targeting with plasma membrane. Extended in the BTK kinase family by a region designated Tec homology domain, which has roughly 80 residues preceding SH3 domain.
|
|
Alternative Nomenclature
|
Agammaglobulinaemia tyrosine kinase antibody
AGMX 1 antibody
AT antibody
ATK antibody
B cell progenitor kinase antibody
BPK antibody
Bruton tyrosine kinase antibody
Btk antibody
IMD1 antibody
PSCTK 1 antibody
Tyrosine protein kinase BTK antibody
XLA antibody
|
BTK Antibody
BTK Antibody BIOTIN
BTK Blocking Peptide
BTK Positive Control
