General Information
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Product
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C9orf72 Antibody
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Verified Applications
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DB, ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 100-200 on human C9orf72 isoform a protein.
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Specificity |
Will detect both long and short C9orf72 isoforms in human and other species. |
Accession #
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NCBI: NP_001242983.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.68-0.70 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:4,000
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ELISA
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1:4,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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Q96LT7
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Overview
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May play a role in endosomal trafficking and autophagy
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Molecular Function
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Autophagy; endocytosis; cell death
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Subcellular Location
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Nucleus; Cytoplasm; Endosome; Lysosome; Autophagosome; Secreted
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Expression
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Both isoforms are widely expressed including kidney, lung, liver, heart, testis, cerebellum, frontal cortex and lymphoblasts.
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Structure
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Interacts with small Rab GTPases including RAB1A and RAB7A
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Alternative Nomenclature
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mALSFTD Antibody
chromosome 9 open reading frame 72 antibody
FTDals antibody
MGC23980 antibody
RP11-27J8.2 antibody
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