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General Information
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Product
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CAMKII gamma Antibody
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Description
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Affinity Purified Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 3 Antibody N-epitope
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Verified Applications
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CM, DB, ELISA, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 350-400 on human CAMKII gamma protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.8 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:200
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:200
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Immunofluorescence
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1:200
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Immunohistochemistry
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1:200
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q13555
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Overview
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Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.
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Molecular Function
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Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase
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Subcellular Location
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Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
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Expression
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Skeletal muscle
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Structure
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CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of t
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Alternative Nomenclature
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Calcium/calmodulin dependent protein kinase type 1G antibody
CaM kinase I gamma antibody
CaM kinase IG antibody
CaMK-like CREB kinase III antibody
Camk1g antibody
CLICK III antibody
VWS1 antibody
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CaMKII gamma Antibody FITC
CaMKII gamma Antibody BIOTIN
CaMKII gamma Blocking Peptide
CaMKII gamma Positive Control
