General Information
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Product
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Calcium Sensing Receptor Antibody
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Description
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Affinity Purified extracellular calcium-sensing receptor Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
Predicted: Rabbit, Horse, Chicken, Cow, Dog, Chimpanzee, Macaque Monkey
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Immunogen
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Synthetic peptide corresponding to amino acids 47-69 on human CASR gene.
Sequence:
KDQDLKSRPESVECIRYNFRGFR
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Accession #
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NCBI: NP_000379.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.7 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant |
N-epitope |
Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:150 |
Western Blot
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1:500. Predicted molecular weight: 121 kDa
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Protein
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Uniprot #
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P41180
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Overview
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Senses change in extracellular concentration of calcium channels.
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Molecular Function
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GPCR, Receptor, Transducer.
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Subcellular Location
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Cell membrane; Mulipass membrane protein.
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Expression
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Temporal lobe, frontal lobe, parietal lobe, hippocampus, cerebellum, kidney, lung, liver, heart, skeletal muscle and placenta.
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Structure
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Interacts with VCP, RNF19A and ARRB1.
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Alternative Nomenclature
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CAR antibody
EIG8 antibody
FHH antibody
FIH antibody
GPRC2A antibody
HHC1 antibody
Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody
NSHPT antibody
Parathyroid Cell calcium-sensing receptor antibody
PCAR1 antibody
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