Calcium Sensing Receptor Antibody

General Information

Product

Calcium Sensing Receptor Antibody

Description

Affinity Purified extracellular calcium-sensing receptor Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Predicted: Rabbit, Horse, Chicken, Cow, Dog, Chimpanzee, Macaque Monkey

Immunogen

Synthetic peptide corresponding to amino acids 47-69 on human CASR gene.

Sequence:

KDQDLKSRPESVECIRYNFRGFR

Accession #

NCBI: NP_000379.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500. Predicted molecular weight: 121 kDa

Protein

Uniprot #

P41180

Overview

Senses change in extracellular concentration of calcium channels.

Molecular Function

GPCR, Receptor, Transducer.

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

Temporal lobe, frontal lobe, parietal lobe, hippocampus, cerebellum, kidney, lung, liver, heart, skeletal muscle and placenta.

Structure

Interacts with VCP, RNF19A and ARRB1.

Alternative Nomenclature

CAR antibody

EIG8 antibody

FHH antibody

FIH antibody

GPRC2A antibody

HHC1 antibody

Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody

NSHPT antibody

Parathyroid Cell calcium-sensing receptor antibody

PCAR1 antibody