CCR1 Antibody

General Information

Product

CCR1 Antibody

Description

Affinity Purified Chemokine (C-C motif) receptor 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on mouse CCR1 protein.

Accession #

GenBank: AAH64991

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P32246

Overview

C-C type chemokine receptor that binds MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3.  Also binds less efficiently to MIP-1-beta or MCP-1.  Subsequently transduces a signal by increasing the intracellular calcium ion level.  Also responsible for affecting stem cell proliferation.

Molecular Function

GPCR; Receptor; Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Hematopoietic cells

Structure

Belongs to G-protein coupled receptor 1 family.  Interacts with CREB3.

Alternative Nomenclature

C C chemokine receptor type 1 antibody

C C CKR 1 antibody

CCR-1 antibody

CD191 antibody

Chemokine C C motif receptor 1 antibody

CKR 1 antibody

CMKBR1 antibody

CMKR 1 antibody

HM145 antibody

LD78 receptor antibody

Macrophage inflammatory protein 1 alpha receptor antibody

RANTES R antibody

SCYAR1 antibody