Sialoadhesin Antibody FITC

Product no.: CD169-FITC
$375.00


General Information

 

 

Product

 

Sialoadhesin Antibody FITC

Description

FITC-Conjugated CD169 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 10-60 on human Sialoadhesin protein.

Accession #

NCBINP_075556


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

FITC-Conjugated

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

ELISA

 

1:10,000

Immunohistochemistry 1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:500


Protein

 

Uniprot #

 

Q9BZZ2

Overview

Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells.Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hemopoiesis.

Molecular Function

Carbohydrate binding; Cell adhesion; Endocytosis

Subcellular Location

Isoform 1: Cell membrane; Isoform 2: Secreted

Expression

Expressed by macrophages in various tissues. High levels are found in spleen, lymph node, perivascular macrophages in brain and lower levels in bone marrow, liver Kupffer cells and lamina propria of colon and lung. Also expressed by inflammatory macrophagrophages in rheumatoid arthritis.

Structure

Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Contains 16 Ig-like C2-type (immunoglobulin-like) domains.

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Alternative Nomenclature

CD169 antibody

dJ1009E24.1 antibody

DKFZp667F058 antibody

sialic acid binding Ig-like lectin 1, sialoadhesin antibody

Sialic acid-binding Ig-like lectin 1 antibody

Sialoadhesin antibody

Siglec 1 antibody

SN antibody

   

Protein information supplied by UniProt
 

 

1:200

Accessories

Product Note Status Price
Sialoadhesin Positive Control Sialoadhesin Positive Control
PC-CD169 $200.00 *
Sialoadhesin Blocking Peptide Sialoadhesin Blocking Peptide
P-CD169 $155.00 *
Sialoadhesin Antibody BIOTIN Sialoadhesin Antibody BIOTIN
CD169-BIOTIN $375.00 *
Sialoadhesin Antibody Sialoadhesin Antibody
CD169-101AP $285.00 *
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