CD47 Antibody

Product no.: CD47-101AP

$285.00

Description

General Information
Product	CD47 Antibody
Description	Affinity Purified Leukocyte surface antigen CD47 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse Predicted: Rat
Immunogen	Synthetic peptide taken within amino acid region 100-150 on human CD47 protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q08722
Overview	Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Molecular Function	Thrombospondin receptor activity; Cell adhesion
Subcellular Location	Cell membrane, Membrane
Expression	Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.
Structure	Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Alternative Nomenclature	Antigen identified by monoclonal antibody 1D8 antibody Antigenic surface determinant protein OA3 antibody CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody CD47 glycoprotein antibody CD47 molecule antibody IAP antibody Integrin Associated Protein antibody Integrin associated signal transducer antibody Leukocyte surface antigen CD47 antibody MER6 antibody OA3 antibody Protein MER6 antibody Rh related antigen antibody

Protein information supplied by UniProt