C6orf150 Antibody

Product no.: CGAS-101AP

$320.00

General Information
Product	C6orf150 Antibody
Description	Affinity Purified Cyclic GMP-AMP synthase Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 450-500 on mouse cGAS protein.
Accession #	NCBI: NP_775562
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.60 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:100
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q8C6L5
Overview	Catalyzes the formation of cyclic GMP-AMP from ATP and GTP. Has antiviral activity through acting as a cystolic DNA senser.
Molecular Function	Nucleotidyltransferase; ATP binding; DNA binding
Subcellular Location	Cytoplasm; Cytosol
Expression	Is expressed in the monocytic cell line THP1 by type 1 Interferons
Structure	Monomer when in absence of DNA. Homodimer when bound to DNA.
Alternative Nomenclature	C6orf150 antibody cGAMP synthase antibody cGAS antibody Chromosome 6 open reading frame 150 antibody Cyclic GMP-AMP synthase antibody h-cGAS antibody Hypothetical protein LOC115004 antibody Mab 21 domain containing 1 antibody MB21D1 antibody protein MB21D1 antibody Uncharacterized protein C6orf150 antibody

Protein information supplied by UniProt