|
General Information
|
|
|
Product
|
Calponin Antibody
|
|
Description
|
Affinity Purified Calponin 1, basic, smooth muscle Antibody N-epitope
|
|
Verified Applications
|
ELISA, IHC, IP, WB
|
|
Host
|
Rabbit
|
|
Species Cross Reactivity
|
Human, Monkey, Mouse, Rat
|
|
Immunogen
|
Synthetic peptide taken within amino acid region 120-170 on human Calponin 1, basic, smooth muscle protein.
|
|
Accession #
|
NCBI: XP_005259798.1
|
|
Physical Properties
|
|
|
Quantity
|
100 µg
|
|
Volume
|
200 µl
|
|
Concentration
|
0.55-0.75 µg/µl in antibody stabilization buffer
|
|
Form
|
Affinity Purified
|
|
Clonality
|
Polyclonal
|
|
Determinant
|
N-epitope
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
DB
|
1:10,000
|
|
ELISA
|
1:10,000
|
|
Immunoprecipitation
|
1:150
|
| Immunohistochemistry |
1:200 |
|
Western Blot
|
1:500
|
|
Protein
|
|
Uniprot #
|
B7Z7E1
|
|
Overview
|
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
|
|
Molecular Function
|
Actin-Binding; actomyosin structure organization
|
|
Subcellular Location
|
Cytoskeleton; Focal Adhesion
|
|
Expression
|
Smooth muscle, and tissues containing significant amounts of smooth muscle.
|
|
Structure
|
Belongs to the calponin family.UniRule annotation
Contains 1 CH (calponin-homology) domain.
Contains 3 calponin-like repeats.
|
|
Alternative Nomenclature
|
Basic calponin antibody
Calponin 1 antibody
Calponin 1 basic smooth muscle antibody
Calponin H1 antibody
Calponin H1 smooth muscle antibody
Calponins basic antibody
CNN 1 antibody
Sm Calp antibody
SMCC antibody
smooth muscle antibody
|
| |
|
Calponin Antibody FITC
Calponin Antibody BIOTIN
Calponin Blocking Peptide
Calponin Positive Control
