CRMP2 Antibody

Product no.: CRMP2-201AP
$295.00
$265.00


General Information

 

 

Product

 

CRMP2 Antibody

Description

Affinity Purified Collapsin response mediated protein 2 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken from within the region corresponding to AA 60-115 of the CRMP2 protein. The 26mer peptide was conserved in several other species. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero-bifunctional cross linker for immunogen preparation.

Accession #

NCBI: NP_001184222.1


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage

Storage buffer

pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: Tris glycine, Tris HCl, 30% Glycerol, 0.5% BSA, HEPES


Application Protocol

 

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500. Detects a band of approximately 64 kDa in PC-CRMP2 samples. In Jurkat cells, the antibody labels a smaller band (MW 54-56 kDa), the identity of this protein is not known, but may represent a splice variant or proteolysis product of CRMP2 protein.


Protein

 

 

Uniprot #

 

Q16555

Overview

Involved in neuronal development and polarity, axon growth and guidance,  neuronal growth cone collapse,  and cell migration.  Is needed for signalling by class 3 semaphorins and later remodeling of the cytoskeleton.

Molecular Function

Dihydropyrimidinase activity; developmental protein

Subcellular Location

Cytoplasm; Cytoskeleton; Membrane

Expression

Ubiquitous

Structure

Homotetramer and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5.  Intteracts via its C-terminus with the C-terminus of CYF1P1/SRA1.  Also interacts with HTR4, CLN6 and MICALL1.

Alternative Nomenclature

CRAM antibody

DHPRP 2 antibody

Dihydropyrimidinase 2 antibody

DPYL 2 antibody

Musunc 33 antibody

N2A3 antibody

TOAD 64 antibody

ULIP 2 protein antibody

Unc-33-like phosphoprotein 2 antibody

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
CRMP2 Antibody FITC CRMP2 Antibody FITC
CRMP2-FITC $350.00 *
CRMP2 Antibody BIOTIN CRMP2 Antibody BIOTIN
CRMP2-BIOTIN $350.00 *
CRMP2 Blocking Peptide CRMP2 Blocking Peptide
P-CRMP2 $145.00 *
CRMP2 Positive Control CRMP2 Positive Control
PC-CRMP2 $185.00 *
Display accessory details

We also recommend

CRMP1-101AP
CRMP1 Antibody
$265.00 *

Browse these categories as well: Alzheimer's Research, Neurogenesis & Plasticity, Primaries, Cytoskeleton / ECM, Developmental Biology