beta Catenin Antibody


beta Catenin Antibody

Product no.: CTNNB-101AP
$295.00
$265.00


General Information

 

 

Product

 

beta Catenin Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid region 50-100 on human beta CTNNB protein.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20C for long term storage


Application Protocol

 

Dot Blot

1:10,000

ELISA

1:10,000

Immunohistochemistry 1:50-1:100
Immunoprecipitation 1:150

Western Blot

1:500


Protein

 

 

Uniprot #

 

P35222 

Overview

Major downstream component of the canonical Wnt signalling pathway.  Also involved in the regulation of cell adhesion and acts as a negative regulator of centrosome cohesion.

Molecular Function

Activator; Alpha-catenin binding; Cadherin binding; signal transducer activity

Subcellular Location

Cytoplasm; Nucleus; Cell junction; Cell Membrane

Expression

Expressed in hair follicle cell types including basal and peripheral matrix cells as well as cells of the outer and inner root sheaths.  Also expressed in colon and is present in cortical neurons at protein level.

Structure

Two separate complex associated pools found in cytoplasm, majority as compenent of an E-cadheren/catenin adhesion complex.  Another cytoplasmic pool is a part of a large complex which holds AXIN1, AXIN2, APC, CSNK1A1 and GSK3B

Alternative Nomenclature

Cadherin associated protein antibody

Catenin (cadherin associated protein), beta 1, 88kDa antibody

CATNB antibody

CHBCAT antibody

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
beta Catenin Antibody FITC beta Catenin Antibody FITC
CTNNB.1-FITC $350.00 *
beta Catenin Antibody BIOTIN beta Catenin Antibody BIOTIN
CTNNB.1-BIOTIN $350.00 *
beta Catenin Blocking Peptide beta Catenin Blocking Peptide
P-CTNNB.1 $145.00 *
beta Catenin Positive Control beta Catenin Positive Control
PC-CTNNB $185.00 *
Display accessory details

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