CXCR1 Antibody

Product no.: CXCR1-112AP

$285.00

Description

General Information
Product	CXCR1 Antibody
Description	Affinity Purified IL-8 receptor type A Antibody C-epitope
Verified Applications	ELISA, ICC/IF, IHC-P, IP
Host	Rabbit
Species Cross Reactivity	Human
Immunogen	Synthetic peptide, corresponding to a region within C terminal amino acids 272-350 of Human CXCR1.
Accession #	GenBank: BAA92293.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	5-.75 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:100-1:1000
Immunofluorescence	1:100-1:1000
Immunoprecipitation	1:250
Western Blot	1:500. Predicted molecular weight: 40 kDa.
Protein
Uniprot #	P25024
Overview	Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Molecular Function	Chemotaxis
Subcellular Location	Cell membrane; Multi-pass membrane protein
Structure	Belongs to the G-protein coupled receptor 1 family
Alternative Nomenclature	C C antibody C C CKR 1 antibody C-X-C chemokine receptor type 1 antibody CCCKR1 antibody CD 181 antibody CD128 antibody CKR 1 antibody CMKAR1 antibody CXC-R1 antibody High affinity interleukin-8 receptor A antibody IL 8 receptor type 1 antibody IL 8R A antibody

Protein information supplied by UniProt