General Information
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Product
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Cyclin D1 Antibody Affinity Purified
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Description
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Affinity Purified G1/S-specific cyclin-D1 Antibody C-epitope
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide corresponding to amino acid sequences 280-295 on human Cyclin D1 protein.
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Accession #
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GenBank: AAH23620.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.65-0.70 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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P24385
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Overview
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Regulatory component of the cyclin D1-CDK4 complex that phosphorylates and inhibits members of retinoblastoma protein family including RB1 and regulates the cell-cycle during G1/S transition.
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Molecular Function
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Cell cycle; Cell division; DNA damage; Transcription regulation
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Subcellular Location
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Cytoplasm; Membrane; Nucleus
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Structure
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Belongs to the Cyclin D subfamily. Contains 1 cyclin N-terminal domain
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Alternative Nomenclature
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B cell CLL/lymphoma 1 antibody
CCND 1 antibody
Cyl 1 antibody
G1/S specific cyclin D1 antibody
Parathyroid adenomatosis 1 antibody
PRAD1 antibody
U21B31 antibody
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