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General Information
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Product
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DAP Kinase 1 Antibody
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Description
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Affinity Purified Death-associated protein kinase 1 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 1370-1420 on human Death-associated protein kinase 1 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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| Immunohistochemistry |
1:50-1:200 |
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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P53355
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Overview
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Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy.
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Molecular Function
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ATP binding
calmodulin binding
calmodulin-dependent protein kinase activity
GTP binding
identical protein binding
protein kinase activity
protein serine/threonine kinase activity
syntaxin-1 binding
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Subcellular Location
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Cytoskeleton
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Expression
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Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas.
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Structure
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The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core.
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Alternative Nomenclature
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DAK1 antibody
DAP K1 antibody
DAP kinase 1 antibody
DAPK antibody
DAPK1 antibody
Death Associated Protein Kinase 1 antibody
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DAP Kinase 1 Antibody BIOTIN
DAP Kinase 1 Positive Control
DAP Kinase 1 Blocking Peptide
DAP Kinase 1 Antibody FITC
