DCC Antibody

Product no.: DCCR-101AP

$285.00

Description

General Information
Product	DCC Antibody
Description	Affinity Purified Netrin Receptor DCC Antibody
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1330-1380 on rat DCC protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5-.70 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20°C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	P43146
Overview	Receptor for netrin required for axon guidance; may trigger signaling for axon repulsion; acts as a dependence receptor required for apoptosis induction; tumor suppressor gene.
Molecular Function	netrin receptor activity; transcription coactivator activity; transmembrane signaling receptor activity; Developmental protein
Subcellular Location	axon; cytosol; plasma membrane
Expression	Found in axons of the central and peripheral nervous system; differentiated cell types of the intestine
Structure	Belongs to the immunoglobulin superfamily. DCC family; Contains 6 fibronectin type-III domains; Contains 4 Ig-like C2-type (immunoglobulin-like) domains
Alternative Nomenclature	Colorectal cancer related chromosome sequence 18 antibody CRC 18 antibody CRCR 1 antibody DCC antibody Deleted in colorectal cancer protein antibody Immunoglobulin superfamily DCC subclass member 1 antibody Netrin receptor DCC antibody Tumor suppressor protein DCC antibody

Protein information supplied by UniProt