General Information
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Product
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E2F2 Antibody Affinity Purified
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Description
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Affinity Purified Transcription Factor E2F2 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 70-120 on E2F2 protein.
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Accession #
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NCBI: NP_808401.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.75-1.25 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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P56931
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Overview
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Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication
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Molecular Function
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core promoter binding; sequence-specific DNA binding transcription factor activity.
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Subcellular Location
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Nucleus
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Expression
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developing epidermis and intestinal epithelium;thymus; liver;nervous system
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Structure
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Component of the DRTF1/E2F transcription factor complex. Forms heterodimers with DP family members
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Alternative Nomenclature
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dE2F2 antibody
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