General Information
|
|
Product
|
E2F3 Antibody
|
Description
|
Affinity Purified Transcription Factor E2F3 Antibody
|
Verified Applications
|
ELISA, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Mouse
|
Immunogen
|
Synthetic peptide taken within amino acid region 70-120 on E2F3 protein.
|
Accession #
|
GenBank: CAI24679.1
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.78-0.89 µg/µl in antibody stabilization buffer
|
Form
|
Affinity Purified
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunoprecipitation
|
1:200
|
Western Blot
|
1:500
|
Protein
|
|
Uniprot #
|
O35261
|
Overview
|
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication
|
Molecular Function
|
core promoter binding; sequence-specific DNA binding transcription factor activity.
|
Subcellular Location
|
Nucleus
|
Expression
|
developing nervous system;spinal cord
|
Structure
|
Component of the DRTF1/E2F transcription factor complex
|
Alternative Nomenclature
|
DKFZp686C18211 antibody
KIAA0075 antibody
MGC104598 antibody
|