EFEMP1 Antibody

Product no.: EFP-101AP

$285.00

Description

General Information
Product	EFEMP1 Antibody
Description	Affinity Purified EGF-containing fibulin-like extracellular matrix protein 1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey, Mouse, Rat
Immunogen	Synthetic cyclic peptide corresponding to N terminal amino acids 25-42 of Human EFEMP1, peptide was covalently modified. Sequence: TYTQCTDGYEWDPVRQQC
Accession #	NCBI: XP_005264262.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.65 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500. Predicted molecular weight 60 kDa
Protein
Uniprot #	UPI000387D485
Overview	Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Molecular Function	Calcium
Subcellular Location	Secreted; Extracellular space
Expression	In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina.
Structure	Interacts with ECM1. Interacts with TIMP3.
Alternative Nomenclature	DHRD antibody Doyne honeycomb retinal degeneration antibody DRAD antibody EFEMP 1 antibody Epidermal growth factor containing fibulin like extracellular matrix protein 1 antibody FBLN3 antibody Fibrillin like antibody FIBULIN 3 antibody FLJ35535 antibody Heat shock 70 KD protein 1 antibody MGC111353 antibody MLVT antibody T16 protein antibody

Protein information supplied by UniProt