ELOVL4 Antibody

General Information

Product

ELOVL4 Antibody

Description

Affinity Purified Elongation of very long chain fatty acids protein 4 Antibody

N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Cat, Rat

Immunogen

Synthetic peptide corresponding to amino acids 2-22 of Human ELOVL4 protein.

Sequence:

GLLDSEPGSVLNVVSTALNDT

Accession #

NCBI:  NP_073563

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q9GZR5

Overview

Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development.

Molecular Function

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Subcellular Location

Endoplasmic Reticulum; Membrane

Expression

Expressed in the retina and at much lower level in the brain. Ubiquitous, highest expression in thymus, followed by testis, small intestine, ovary, and prostate. Little or no expression in heart, lung, liver, or leukocates.

Structure

The di-lysine motif may confer endoplasmic reticulum localization.

Alternative Nomenclature

3-keto acyl-CoA synthase ELOVL4 antibody

ADMD antibody

Cancer/testis antigen 118 antibody

CT118 antibody

Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 4 antibody

ELOV L4 antibody

Stargardt disease 3 antibody

STGD2 antibody

STGD3 antibody