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General Information
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Product
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PTGER3 Antibody
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Description
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Protaglandin Receptor EP3D Antibody
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Verified Applications
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CM, ELISA, ICC/IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse
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Immunogen
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Synthetic peptide corresponding to unique amino acid sequence on EP3 Receptor protein.
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Accession #
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NCBI: XP_009209142.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-0.6 µg/µl in antibody stabilization buffer
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:250
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:250
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Immunofluorescence
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1:250
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Immunohistochemistry
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1:250
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Immunoprecipitation
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1:250
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Western Blot
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1:500
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Protein
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Uniprot #
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UPI0004F2137B
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Overview
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Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
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Molecular Function
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Prostaglandin E receptor activity, G-protein coupled receptor
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Subcellular Location
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Cell membrane; Multi-pass membrane
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Expression
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Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
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Structure
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Belongs to the G-protein coupled receptor 1 family.
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Alternative Nomenclature
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EP 3 antibody
EP3 I antibody
EP3 II antibody
EP3 III antibody
EP3 IV antibody
Ep3 prostanoid receptor antibody
Ep3 receptor antibody
EP3 subtype antibody
EP3e antibody
MGC141828 antibody
MGC141829 antibody
PGE receptor EP3 subtype antibody
PGE2 R antibody
Pgerep3 antibody
Prostaglandin E receptor EP3 subtype 3 isoform antibody
Prostanoid EP3 receptor antibody
PTGER 3 antibody
Rep3 antibody
rEP3a antibody
rEP3b antibody
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PTGER3 Antibody FITC
PTGER3 Antibody BIOTIN
PTGER3 Blocking Peptide
PTGER3 Positive Control
