ergo-1 Antibody

Product no.: ERGO-112AP

$285.00

Description

General Information
Product	ergo-1 Antibody
Description	Affinity Purified Endogenous-RNAi deficient arGOnaute antibody N-epitope
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Caenorhabditis elegans
Immunogen	Synthetic peptide taken within amino acid region 790-840 on C.elegans Endogenous-RNAi deficient arGOnaute protein.
Accession #	NCBI: NP_503362.2
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.62-0.68 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	O61931
Overview	Argonaute protein required for gene silencing in the endogenous RNA interference (RNAi) pathway. Interacts with 26G small interfering RNAs (26G-siRNAs) and required for subsequent biogenesis of secondary 22G-siRNAs. May be involved in passenger strand cleavage of target 26G-siRNAs (PubMed: 22102828).
Molecular Function	Dead/H-box RNA helicase binding, nucleic acid binding, production of siRNA involved in RNA interference, regulation of translation, RNA interference.
Subcellular Location	Cytoplasm
Structure	Belongs to the argonaute family. Piwi subfamily. Contains 1 PAZ domain. Contains 1 Piwi domain.
Expression	Expressed in embryos and during larval development up to larval stage 2.
Alternative Nomenclature	Endogenous RNAi deficient argonaute antibody Ergo 1 antibody Hypothetical protein R09A1.1 antibody

Protein information supplied by by UniProt