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General Information
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Product
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FXIIIA Antibody
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Description
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Affinity Purified Blood coagulation factor XIII a subunit Antibody N-epitope
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Cat, Human, Monkey, Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 1-50 on human factor XIII A subunit protein.
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Accession #
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GenBank: AAA52415.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P00488
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Overview
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Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
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Molecular Function
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Metal ion binding; Protein-glutamine gamma-glutamyltransferase activity
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Subcellular Location
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Cytoplasm. Secreted
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Structure
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Tetramer of two A chains and two B chains.
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Alternative Nomenclature
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bA525O21.1 (coagulation factor XIII, A1 polypeptide) antibody
Coagulation factor XIII A chain antibody
F13A antibody
F13A1 antibody
Fibrin stabilizing factor, A subunit antibody
Fibrinoligase antibody
FSF, A subunit antibody
FXIIIA antibody
Protein-glutamine gamma-glutamyltransferase A chain antibody
TGase antibody
Transglutaminase A chain antibody
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FXIIIA Antibody FITC
FXIIIA Antibody BIOTIN
FXIIIA Blocking Peptide
FXIIIA Positive Control
