GR28B Antibody

General Information

Product

GR28B Antibody

Description

Affinity Purified Gustatory receptor 28b Antibody

Verified Applications

ELISA, IP, WB

Host

Chicken

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Synthetic peptide taken within amino aid region 1-60 on drosophila melanogaster (fruit fly) Gustatory receptor 28b.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgY

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20?C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500-1:5,000

Protein

Uniprot #

Q9VM08

Overview

Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression suggests also nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands.

Molecular Function

taste receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Isoforms A and E have taste neuron-specific expression restricted to the labial palps, the internal taste organs in the pharynx, and the legs. In addition to expression in a large number of taste neurons, isoform A is also expressed in a few nonchemosensory neurons, including the campaniform sensilla of the wing, leg stretch receptors, and multiple dendritic neurons in the abdomen. Isoform B is the only receptor not expressed in gustatory receptor neurons in the labellum.

Structure

Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr66a subfamily.

Alternative Nomenclature

CG13788

Gr28b

Gustatory receptor 28b

Putative gustatory receptor 28b