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General Information
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Product
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GTP cyclohydrolase 1 Antibody
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Description
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Affinity Purified GTP cyclohydrolase 1 Antibody C-epitope
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 25-75 on mouse GTPCHI protein.
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Accession #
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GeneBank: AAH05643
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.73-1.01 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:20,000
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ELISA
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1:20,000
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| Immunohistochemistry |
1:100 |
| Immunoprecipitation |
1:200 |
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Western Blot
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1:500-1:750
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Protein
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Uniprot #
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Q05915
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Overview
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Positively regulates nitric oxide synthesis in endothelial cells. Invovled in dopamine synthesis and pain sensitivity and persistence.
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Molecular Function
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Cofactor biosynthesis; GTP binding; Coenzyme binding; Calcium ion binding
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Subcellular Location
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Cytoplasm; Nucleus
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Structure
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Toroid-shaped homodecamer. Composed of two pentamers of five dimers.
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Alternative Nomenclature
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dystonia 14 antibody
DYT 5 antibody
DYT14 antibody
DYT5a antibody
GCH antibody
GTP CH 1 antibody
GTP cyclohydrolase 1 (dopa responsive dystonia) antibody
Guanosine 5' triphosphate cyclohydrolase I antibody
HPABH4B antibody
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GTP cyclohydrolase 1 Antibody FITC
GTP cyclohydrolase 1 Antibody BIOTIN
GTP cyclohydrolase 1 Blocking Peptide
GTP cyclohydrolase 1 Positive Control
