HIF-1-Alpha isoform 1 Antibody

General Information

Product

HIF-1-Alpha isoform 1 Antibody

Description

Affinity Purified Hypoxia-inducible factor 1-alpha isoform 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 790-826 on human HIF1A protein.

Accession #

NCBI:  NP_001521.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q16665

Overview

Functions as a master transcriptional regulator of the adaptive response to hypoxia.

Molecular Function

Activator

Subcellular Location

Cytoplasm, Nucleus

Expression

highest levels in kidney and heart;common human cancers and their metastases, due to the presence of intratumoral hypoxia

Structure

Heterodimer

Alternative Nomenclature

ARNT interacting protein antibody

Basic-helix-loop-helix-PAS protein MOP1 antibody

bHLHe78 antibody

Class E basic helix-loop-helix protein 78 antibody

HIF 1A antibody

HIF 1alpha antibody

Hypoxia inducible factor 1 alpha antibody

Member of PAS protein 1 antibody

Member of PAS superfamily 1 antibody

MOP1 antibody

PAS domain-containing protein 8 antibody

PASD8 antibody