Insulin degrading enzyme Antibody

Product no.: IDE-101AP

General Information

 

 

Product

 

Insulin degrading enzyme Antibody

Verified Applications

ELISA, IP WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human Insulin-degrading enzyme protein.

Accession #

GenBank: EAW50092.1


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500


Protein

 

Uniprot #

 

UPI00002289E9

Overview

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Molecular Function

ATPase activity; Ubiquitin Binding; Zinc ion binding; Insulin binding; Hydrolase; Metalloprotease; Protease

Subcellular Location

Cytoplasm; Cell membrane; Secreted

Structure

Homodimer. Can form higher oligomers. Interacts (via N-terminus) with varicella-zoster virus (VZV) envelope glycoprotein E (via N-terminus); the membrane-associated isoform may function as an entry receptor for this virus.

Alternative Nomenclature

Abeta-degrading protease antibody

FLJ35968 antibody

Ide antibody

insulin protease antibody

Insulin-degrading enzyme antibody

insulinase antibody

insulysin antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
Insulin degrading enzyme Antibody FITC Insulin degrading enzyme Antibody FITC
IDE-FITC
Insulin degrading enzyme Antibody BIOTIN Insulin degrading enzyme Antibody BIOTIN
IDE-BIOTIN
Insulin degrading enzyme Blocking Peptide Insulin degrading enzyme Blocking Peptide
P-IDE
Insulin degrading enzyme Positive Control Insulin degrading enzyme Positive Control
PC-IDE
Display accessory details

Browse these categories as well: Alzheimer's Research, Insulin, Neurodegenerative Disease, Growth Factors, Growth Factors & Hormones, Diabetes, Metabolism, Metabolism & Homeostasis, Metalloprotease, Cardiology, Primaries, Ubiquitination and Proteinases