IFI16 Antibody

Product no.: IFI16H-101AP
$295.00
$265.00


General Information

 

 

Product

 

IFI16 Antibody Affinity Purified

Description

Affinity Purified Gamma-interferon-inducible protein 16 isoform 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 140-190 on human IFI16 protein

Accession #

NCBINP_001193496.1


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.58-0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500


Protein

 

Uniprot #

 

Q16666

Overview

Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein.

Molecular Function

Core promoter binding, identical protein binding, transcription factor binding, double-standard DNA binding, poly(A) RNA binding

Subcellular Location

Nucleus, cytoplasm (Note: Cellular distribution is dependent on acetylation status of multipartite nuclear localization signal(NLS); NLS acetylation promotes cytoplasmic localization. Localizes in nucleus during human herbes simplex virus 1 infection)

Expression

Expressed in peripheral blood leukocytes, fibroblasts and lymphoid cells. Present in myeloid precursors (CD34+) and throughout monocyte development, but its expression is down-regulated in erythroid and polymorphonuclear precursor cells. Present in prosta

Alternative Nomenclature

IFI16 antibody

Gamma interferon inducible protein 16 antibody

Ifi204 antibody

IFNGIP1 antibody

interferon activated gene 204 antibody

Interferon gamma inducible protein 16 antibody

p204 antibody

PYHIN2 antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
IFI16 Antibody FITC IFI16 Antibody FITC
IFI16H-FITC $350.00 *
IFI16 Antibody BIOTIN IFI16 Antibody BIOTIN
IFI16H-BIOTIN $350.00 *
IFI16 Blocking Peptide IFI16 Blocking Peptide
P-IFI16H $145.00 *
IFI16 Positive Control IFI16 Positive Control
PC-IFI16H $185.00 *
Display accessory details

We also recommend

IFI27-101AP
IFI27 Antibody
$265.00 *
IFI27-112AP
IFI27 Antibody
$265.00 *
IFI6-101AP
IFI6 Antibody
$265.00 *

Browse these categories as well: p53 Pathway, Diagnostic Markers, Cell Cycle, Cell Cycle, Transcription Factors, Transcription, Oxidative Stress, Primaries