General Information
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Product
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IFI27 Antibody
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Description
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Affinity Purified Interferon, alpha-inducible protein 27 Antibody N-epitope
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Verified Applications
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ELISA, ICC/IF, IHC-Fr, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide: multiple antigenic peptide (8 branch) corresponding to amino acids 2-13 of Human IFI27.
Sequence:
EASALTSSAVTS
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Accession #
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NCBI: NP_005523.3
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.50-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:100,000
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ELISA
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1:100,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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UPI000019A7CD
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Overview
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Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.
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Molecular Function
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Lamin binding; RNA polymerase II activating transcription factor binding
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Subcellular Location
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Mitochondrion; Multi-pass membrane protein
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Expression
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Up-regulated by interferons
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Structure
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Belongs to the IFI6/IFI27 family.
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Alternative Nomenclature
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2310061N23Rik antibody
FAM14D antibody
IFI 27 antibody
Interferon alpha induced 11.5 kDa protein antibody
Interferon inducible protein 27 antibody
interferon-stimulated gene 12 antibody
ISG 12 antibody
ISG12A antibody
P27 antibody
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