General Information
|
|
Product
|
IL17A Antibody
|
Description
|
Affinity Purified Interleukin-17A Antibody
|
Verified Applications
|
CM, ELISA, ICC, IF, IHC, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 110-150 on human Interleukin-17A precursor protein.
|
Specificity |
This antibody is specific for Interleukin-17A and will not cross react with any other Interleukin-17 variants. |
Accession #
|
NCBI: NP_002181
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.65-0.95 µg/µl in antibody stabilization buffer
|
Form
|
Affinity Purified
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Confocal Microscopy
|
1:200
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunocytochemistry
|
1:200
|
Immunofluorescence
|
1:200
|
Immunohistochemistry
|
1:200
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
Q96F46
|
Overview
|
Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
|
Molecular Function
|
interleukin-17 receptor activity
|
Subcellular Location
|
Isoform 1: membrane, single-pass type I membrane protein; Isoform 2: secreted
|
Expression
|
Widely expressed.
|
Alternative Nomenclature
|
CTLA 8 antibody
Cytotoxic T lymphocyte associated serine esterase 8 antibody
IL-17A antibody
IL17 antibody
Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
Interleukin 17A antibody
OTTHUMP00000016597 antibody
OTTMUSP00000046003 antibody
|
|
|