General Information
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Product
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IRAK1 Antibody
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Description
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Affinity Purified Interleukin-1 receptor-associated kinase 1 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid reigon 700-750 on mouse Interleukin-1 receptor-associated kinase 1 protein.
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Accession #
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NCBI: NP_001171444
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polylclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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B1AUW6
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Molecular Function
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ATP binding
heat shock protein binding
kinase activity
NF-kappaB-inducing kinase activity
protein heterodimerization activity
protein homodimerization activity
protein kinase activity
protein serine/threonine kinase activity
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Subcellular Location
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Nucleus, Cytoplasm, Lipid droplet
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Expression
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Isoform 1 and isoform 2 are ubiquitously expressed in all tissues examined, with isoform 1 being more strongly expressed than isoform 2.
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Structure
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Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
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Alternative Nomenclature
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Il1rak antibody
Interleukin 1 receptor associated kinase 1 antibody
IRAK antibody
Irak1 antibody
mPLK antibody
Pelle antibody
Pelle homolog antibody
Plpk antibody
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