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General Information
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Product
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IRAKM Antibody
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Description
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Affinity Purified Interleukin-1 receptor-associated kinase 3 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 450-500 on mouse Interleukin-1 receptor-associated kinase 3 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polylclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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Q9Y616
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Overview
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Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
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Molecular Function
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ATP binding
magnesium ion binding
protein heterodimerization activity
protein homodimerization activity
protein serine/threonine kinase activity
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Subcellular Location
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Nucleus, Cytoplasm
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Expression
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Expressed predominantly in peripheral blood lymphocytes.
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Structure
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Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
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Alternative Nomenclature
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ASRT5 antibody
IL 1 receptor associated kinase M antibody
Interleukin 1 receptor associated kinase 3 antibody
Interleukin 1 receptor associated kinase M antibody
IRAK M antibody
IRAK-3 antibody
IRAK-M antibody
Irak3 antibody
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IRAKM Antibody BIOTIN
IRAKM Positive Control
IRAKM Blocking Peptide
IRAKM Antibody FITC
