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General Information
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Product
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LARP7 Antibody Affinity Purified
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Description
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Affinity Purified LARP7 protein Antibody N-epitope
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Verified Applications
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ELISA, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide taken within amino acid region 300-350 on human LARP7 protein.
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Accession #
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GenBank: AAI07710.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:4,000
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ELISA
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1:4,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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Q4G0J3
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Overview
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Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
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Molecular Function
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RNA-binding; RNA processing
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Subcellular Location
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Nucleus
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Structure
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Integral part of the 7SK RNP complex. Specifically binds to the highly conserved 3'-terminal U-rich stretch of 7SK RNA. On stimulation, remains associated with 7SK RNA, whereas P-TEFb is released from the complex.
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Alternative Nomenclature
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HDCMA18P antibody
La related protein 7 antibody
La ribonucleoprotein domain family member 7 antibody
P TEFb interaction protein for 7SK stability antibody
PIP7S antibody
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LARP7 Antibody FITC
LARP7 Antibody BIOTIN
LARP7 Blocking Peptide
LARP7 Positive Control
