|
General Information
|
|
|
Product
|
LAT Antibody Affinity Purified
|
|
Verified Applications
|
ELISA, WB
|
|
Host
|
Rabbit
|
|
Species Cross Reactivity
|
Human
|
|
Immunogen
|
Synthetic peptide taken within amino acid region 40-90 on LAT protein.
|
|
Accession #
|
Gen Bank: AAC39637.1
|
|
Physical Properties
|
|
|
Quantity
|
100 µg
|
|
Volume
|
200 µl
|
|
Concentration
|
0.54-0.72 µg/µl in antibody stabilization buffer
|
|
Form
|
Affinity Purified
|
|
Clonality
|
Polyclonal
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
DB
|
1:10,000
|
|
ELISA
|
1:10,000
|
|
Western Blot
|
1:500
|
|
Protein
|
|
Uniprot #
|
O43561
|
|
Overview
|
Required for TCR (T-cell antigen receptor) and pre-TCR-mediated signaling both in mature T-cells and during their development.
|
|
Molecular Function
|
Protein kinase binding, SH3/SH2 adaptor activity
|
|
Subcellular Location
|
Cell membrane, single-pass type III membrane protein
|
|
Expression
|
Expressed in thymus, T-cells, NK cells, mast cells and, at lower levels, in spleen. Present in T-cells but not B-cells (at protein level).
|
|
Alternative Nomenclature
|
36 kDa phospho tyrosine adapter protein antibody
LAT 1 antibody
lat antibody
Linker for activation of T cells antibody
p36 38 antibody
pp36 antibody
|
| |
|
LAT Antibody FITC
LAT Antibody BIOTIN
LAT Blocking Peptide
LAT Positive Control
