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General Information
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Product
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NTAL Antibody
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Description
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Affinity Purified Linker for activation of T-cells family member 2 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 40-90 on LAT2 protein.
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Accession #
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NCBI: NP_115852
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.54-0.72 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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| Immunohistochemistry |
1:100 |
| Immunohistochemistry |
1:200 |
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9GZY6
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Overview
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Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells.
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Molecular Function
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SH2 domain binding
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Subcellular Location
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Cell membrane; Single-pass type III membrane protein
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Expression
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Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B-cells, NK cells and monocytes. Absent from T-cells (at protein level).
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Structure
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When phosphorylated, interacts with GRB2. May also interact with SOS1, GAB1 and CBL.
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Alternative Nomenclature
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HSPC046 antibody
LAB antibody
LAT2 antibody
Linker for activation of B cells antibody
Membrane associated adapter molecule antibody
Non T cell activation linker antibody
WBSCR 5 antibody
Wbscr15 antibody
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NTAL Antibody FITC
NTAL Antibody BIOTIN
NTAL Blocking Peptide
NTAL Positive Control
