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General Information
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Product
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MACF1 Antibody
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Description
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Affinity Purified Microtuble-Actin crosslinking factor 1 Antibody
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Verified Applications
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ELISA, ICC, IFC, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse, Rat
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Immunogen
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Recombinant protein
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Accession #
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GenBank: CAM18553.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.7 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunocytochemistry
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1:250
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Immunofluorescence
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1:250
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Immunohistochemistry
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1:250
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9QXZO
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Overview
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F-actin bidning protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds microtubles. Acts as positive regulator of Wnt receptor signaling pathway and is invovled in translocation of AXIN12 and its associated complex from the cytoplasm to cell membrane. Has actin-regulated ATPase activity and is inovled in focal adhesios assembly and dynamics.
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Molecular Function
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Actin binding, calcium ion binding, ATPase activity, microtuble binding
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Subcellular Location
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Hair follicle stem cells; Ubiquitous expression; lung; heart; thymus; spleen; brain.
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Expression
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Expressed in neurontal tissues and foregut of embryo
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Structure
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Complex composed of MACF1, APC, AXIN1, CTNNB1 and GSK3B.
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Alternative Nomenclature
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ABP620 antibody
Acf7 antibody
Aclp7 antibody
Actin cross linking family 7 antibody
MACF antibody
Microtubule actin crosslinking factor 1 antibody
rabeculin alpha antibody
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MACF1 Antibody FITC
MACF1 Antibody BIOTIN
MACF1 Blocking Peptide
MACF1 Positive Control
