MC4 Receptor Antibody

Product no.: MC4R-401AP

$285.00

Description

General Information
Product	MC4 Receptor Antibody
Description	Affinity Purified Melanocortin receptor 4 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 10-60 on human MC4R protein.
Accession #	NCBI: NP_005903.2
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55-0.75 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	P32245
Overview	Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Molecular Function	Melanocortin receptor activity, melanocyte-stimulating hormone receptor activity, neuropeptide binding, ubiquitin protein ligase binding
Subcellular Location	cell membrane, multi-pass membrane protein, membrane raft. (Note: Localizes to membrane rafts but is also loated in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts).
Expression	Brain, placental, and gut tissues.
Alternative Nomenclature	MC4 R antibody Melanocortin receptor 4 antibody MGC126851 antibody MGC138197 antibody

Protein information supplied by UniProt