MeCP2 isoform 1 Antibody

Product no.: MECP2E1-112AP

$285.00

Description

General Information
Product	MeCP2 isoform 1 Antibody
Description	Affinity Purified Methyl-CpG-binding Protein 2 isoform 1 Antibody
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse
Immunogen	Synthetic peptide taken within amino acid region 1-50 on mouse Methyl-CpG-binding Protein 2 isoform 1 protein.
Accession #	NCBI: XP_006538787
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5-1.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Purification Method	Immobilized antigen affinity chromatography
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:50,000
Immunoprecipitation	1:200
Western Blot	1:2,500-1:5,000
Protein
Uniprot #	Q9Z2D6
Overview	Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Molecular Function	chromatin binding DNA binding DNA binding transcription factor activity double-stranded methylated DNA binding methyl-CpG binding mRNA binding protein domain specific binding protein N-terminus binding siRNA binding transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
Subcellular Location	Nucleus
Alternative Nomenclature	AUTSX3 antibody Mbd5 antibody MECP 2 antibody MeCP 2 protein antibody MeCP2 antibody Methyl CpG binding protein 2 (Rett syndrome) antibody Methyl CpG binding protein 2 antibody MRX 16 antibody MRX 79 antibody MRXS13 antibody MRXSL antibody PPMX antibody RS antibody RTS antibody RTT antibody WBP10 antibody

Protein information supplied by UniProt.