MRGX1 Antibody

General Information

Product

MRGX1 Antibody Affinity Purified

Description

Affinity Purified Mas-related G-protein coupled receptor member X1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 280-330 on rat MrgX1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.67 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8R4G1

Overview

Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors)

Structure

Belongs to the G-protein coupled receptor 1 family. Mas subfamily

Alternative Nomenclature

G protein coupled receptor MRGX1 antibody

G protein coupled receptor SNSR3 antibody

GPCR antibody

Mas related G protein coupled receptor member X1 antibody

MRGPRX1 antibody

MRGX1 antibody

Sensory neuron specific G protein coupled receptor 3/4 antibody

Seven transmembrane helix receptor antibody

SNSR3 antibody

SNSR4 antibody