General Information
|
|
Product
|
MUC1 Antibody
|
Description
|
Affinity Purified Mucin 1, transmembrane Antibody
|
Verified Applications
|
ELISA, IHC, IP
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Monkey
|
Immunogen
|
Synthetic peptide corresponding to unique amino acid sequence on MUCIN1 protein.
|
Specificity |
Will detect deglycosylated MUCIN1 protein. |
Accession #
|
NCBI: NM_182741.1
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.65 µg/µl in antibody stabilization buffer
|
Form
|
Affinity Purified
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Confocal Microscopy
|
1:200
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunocytochemistry
|
1:200
|
Immunofluorescence
|
1:200
|
Immunohistochemistry
|
1:200
|
Immunoprecipitation |
1:200 |
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P15941
|
Overview
|
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
|
Molecular Function
|
transcription cofactor activity
|
Subcellular Location
|
Cell membrane, Cytoplasm, Membrane, Nucleus, Secreted
|
Expression
|
Expressed on the apical surface of epithelial cells, especially of airway passages, breast and uterus. Also expressed in activated and unactivated T-cells. Overexpressed in epithelial tumors, such as breast or ovarian cancer and also in non-epithelial tumor cells. Isoform 7 is expressed in tumor cells only.
|
Alternative Nomenclature
|
ADMCKD antibody
Breast carcinoma-associated antigen DF3 antibody
CA 15 3 antibody
CD227 antigen antibody
DF3 antigen antibody
EMA antibody
Episialin antibody
Epithelial basement membrane antigen antibody
H23 antigen antibody
KL 6 antibody
MAM 6 antibody
MCD antibody
MCKD1 antibody
MUC 1 antibody
Peanut-reactive urinary mucin antibody
Polymorphic epithelial mucin antibody
Tumor associated epithelial membrane antigen antibody
|
|
|