Nkx2.2 Antibody

Product no.: NKX2-201AP

General Information

 

 

Product

 

Nkx2.2 Antibody

Description

Affinity Purified homeobox protein Nkx-2.2 Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid region 200-250 on human homeobox protein Nkx-2.2.

Accession #

NCBINP_002500


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20C for long term storage


Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunohistochemistry 1:100

Immunoprecipitation

1:150

Western Blot

1:500


Protein

 

Uniprot #

 

O95096

Overview

Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity).

Molecular Function

Chromatin binding; transcription coactivator activity; Developmental Protein; Transcription regulation; brain development

Subcellular Location

Nucleus

Expression

Interacts with OLIG2

Structure

Belongs to the NK-2 homeobox family.  Contains 1 homeobox DNA-binding domain.  The homeodomain is essential for interaction with OLIG2.

Alternative Nomenclature

Homeobox protein NK 2 homolog B antibody

NK 2 homolog B antibody

NK2 homeobox 2 antibody

NK2 transcription factor like protein B antibody

NK2 transcription factor related locus 2 antibody

NKX2-2 antibody

NKX22 antibody

Nkx2b antibody

tinman antibody

   

Protein information supplied by UniProt

Accessories

Product Note Status Price
Nkx2.2 Antibody FITC Nkx2.2 Antibody FITC
NKX2-FITC
Nkx2.2 Antibody BIOTIN Nkx2.2 Antibody BIOTIN
NKX2-BIOTIN
Nkx2.2 Blocking Peptide Nkx2.2 Blocking Peptide
P-NKX2
Nkx2.2 Positive Control Nkx2.2 Positive Control
PC-NKX2
Display accessory details

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