Nogo Antibody

Product no.: NOGO-101AP
$295.00
$265.00


General Information

 

 

Product

 

Nogo Antibody

Description

Affinity Purified Reticulon-4 isoform A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1100-1200 on Nogo AS protein.

Accession #

NCBINP_065393.1


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.59-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunohistochemistry 1:100
Immunoprecipitation 1:200

Western Blot

1:500


Protein

 

Uniprot #

 

Q9NQC3

Overview

Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching.  Regulates neurite fasciculation, branching and extension in the developing nervous system.

Molecular Function

poly(A) RNA binding

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle.   Isoform 2 is widely expressed except for the liver.  Isoform 3 is expressed in brain, skeletal muscle and adipocytes.  Isoform 4 is testis-specific.

Structure

Binds to RTN4R, interacts with Bcl-xl and Bcl-2.  Isoform 2 binds to NGBR and RTN3.  Isoform 2 and Isoform 3 interact with BACE1 and BACE2, interacts with RTN4IP1 and ATL1.

Alternative Nomenclature

1110020G17Rik antibody

AA407876 antibody

AA409940 antibody

AA960376 antibody

ASY antibody

C130026I10Rik antibody

Foocen antibody

Glut4 vesicle 20 kDa protein antibody

Human NogoA antibody

Kiaa0886 antibody

KIAA4153 antibody

MGC116054 antibody

MGC139261 antibody

mKIAA0886 antibody

mKIAA4153 antibody

My043 protein antibody

Nbla00271 antibody

Nbla10545 antibody

Neurite growth inhibitor 220 antibody

Neuroendocrine-specific protein antibody

NI-250 antibody

Nogo A antibody

NOGO antibody

Nogo B antibody

Nogo C antibody

NSP antibody

NSP CL antibody

rat N antibody

Reticulon 4 antibody

Reticulon 5 antibody

RTN X antibody

RTN4 A antibody

RTN4-B1 antibody

Vp20 antibody

   

Protein information supplied by UniProt 

 

Accessories

Product Note Status Price
Nogo Antibody FITC Nogo Antibody FITC
NOGO-FITC $350.00 *
Nogo Antibody BIOTIN Nogo Antibody BIOTIN
NOGO-BIOTIN $350.00 *
Nogo Blocking Peptide Nogo Blocking Peptide
P-NOGO $145.00 *
Nogo Positive Control Nogo Positive Control
PC-NOGO $185.00 *
Display accessory details

Browse these categories as well: Neurodegenerative Disease, Neurogenesis & Plasticity, Apoptosis, Regulation, Primaries