Olig2 Antibody

General Information

Product

Olig2 Antibody

Description

Affinity Purified OLIG2 protein Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to Human Olig2 amino acids 136-156. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to a carrier protein using hetero-bifunctional cross linker for immunogen preparation.

Sequence:

PYAHGPSVRKLSKIATLLLAR

Accession #

GenBank:  AAH36245.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q13516

Overview

Necessary for oligodendrocyte and motor neuron specification in the spinal cord.  In the hindbrain it is  needed in the development of somatic neurons.

Molecular Function

Developmental protein, DNA binding

Subcellular Location

Nucleus; Cytoplasm

Expression

Is expressed in the brain in oligodendrocytes.  Is expressed strongly in oligodendrogliomas with weaker expression in astrocytomas

Structure

Interacts with NKX2-3

Alternative Nomenclature

Basic domain helix loop helix protein class B 1 antibody

BHLHB antibody

bHLHB1 antibody

bHLHe19 antibody

Class B basic helix loop helix protein 1 antibody

class E basic helix loop helix protein 19 antibody

Human protein kinase C binding protein RACK17 antibody

Olig2 antibody

Oligo2 antibody

Oligodendrocyte lineage transcription factor 2 antibody

Oligodendrocyte specific bHLH transcription factor 2 antibody

PRKCBP2 antibody

Protein kinase C binding protein 2 antibody

Protein kinase C binding protein RACK17 antibody

RACK17 antibody