CD56 Blocking Peptide

General Information

Product

CD56 / NCAM Peptide

Description

Antigenic Blocking Peptide Neural Cell Adhesion Molecule 1

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 800-847 on human neural cell adhesion molecule 1.

Accession #

GenBank: EAW67208.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

UPI0000EE39A0

Overview

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane (By similarity).

Molecular Function

Developmental protein; Cell adhesion; Differentiation; Neurogenesis

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Expression

Expressed in the fetal and adult brain as well as in Schwann cell culture. Also detected in adult peripheral tissues.

Alternative Nomenclature

antigen MSK39 identified by monoclonal antibody 5.1H11 antibody

antigen recognized by monoclonal antibody 5.1H11 antibody

CD 56 antibody

CD56 antigen antibody

Cell Adhesion Molecule Neural 1 antibody

MSK39 antibody

N CAM 180 antibody

N-CAM-1 antibody

NCAM 120 antibody

NCAM 140 antibody

NCAM antibody

NCAMC antibody

NCAM1 antibody

Neural cell adhesion molecule 1 antibody

Neural cell adhesion molecule NCAM antibody

OTTHUMP00000235666 antibody