C6orf150 Blocking Peptide

General Information

Product

C6orf150 Peptide

Description

Antigenic Blocking Peptide Cyclic GMP-AMP synthase Antibody C-epitope

Verified Applications

Immunodepletion/Immunocompetition Assay

Peptide Description

Synthetic Peptide

Accession #

NCBI:  NP_612450

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

1:500

Protein

Uniprot #

Q8N884

Overview

Catalyzes the formation of cyclic GMP-AMP from ATP and GTP.  Has antiviral activity through acting as a cystolic DNA senser.

Molecular Function

Nucleotidyltransferase; ATP binding; DNA binding

Subcellular Location

Cytoplasm; Cytosol

Expression

Is expressed in the monocytic cell line THP1 by type 1 Interferons

Structure

Monomer when in absence of DNA.  Homodimer when bound to DNA.

Alternative Nomenclature

C6orf150 antibody

cGAMP synthase antibody

cGAS antibody

Chromosome 6 open reading frame 150 antibody

Cyclic GMP-AMP synthase antibody

h-cGAS antibody

Hypothetical protein LOC115004 antibody

Mab 21 domain containing 1 antibody

MB21D1 antibody

protein MB21D1 antibody

Uncharacterized protein C6orf150 antibody